I recently had the opportunity to see Thank You for Smoking for the second time. It does the rare feat of being a satire that's actually funny. I bet most of the humor in the movie comes from the source novel by Christopher Buckley (which has since been added to my TBR pile).
The story follows Nick Naylor, spokesman for the tobacco lobby. We gain great insight into his world of spin by the voice-over narration as well as the many scenes Nick has with his son. I think other than the source material, the film is made by both the brisk direction from Jason Reitman and the light-hearted yet earnest portrayal of Naylor by Aaron Eckhart.
If you haven't seen it, do yourself a favor and check it out.